compound, isomers, pharmaceutical composition, and methods of inhibiting pde4 and mmp, modulating tnf-alpha production in a mammal, and treating, preventing or controlling a disease or condition

摘要

"Compound, Isomer, Pharmaceutical Composition, and Methods of Inhibiting PDE4 and MMP, of Modulating TNF-Alpha Production in a Mammalian and Treating, Preventing, or Controlling a Disease or Condition". The invention encompasses novel N-alkyl hydroxamic acid isoindolyl compounds, pharmaceutical compositions of these compounds and methods of using these compounds and compositions for the treatment or prevention of various diseases and disorders, for example PDE4-associated diseases.