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reconstituted viral membrane, method for producing a reconstituted viral membrane, and, pharmaceutical composition

机译:重组病毒膜,生产重组病毒膜的方法和药物组合物

摘要

"RECONSTITUTED VIRAL MEMBRANE, METHOD FOR PRODUCING A RECONSTITUTED VIPAL MEMBRANE, AND PHARMACEUTICAL COMPOSITION". The present invention relates to antigen-directed vaccines such as pathogen membrane proteins or tumor cells. The invention further relates to methods of forming reconstituted membrane membranes with membrane fusion activity which are lipid bilayer membranes, preferably containing natural lipids of a virus, a viral fusion protein, one or more optional additional antigens, as well as as amphiphilic adjuvants. Pharmaceutical compositions comprising such reconstituted viral membranes are also part of the invention.
机译:“重构的病毒膜,制备重构的VIPAL膜的方法和药物成分”。本发明涉及抗原导向的疫苗,例如病原体膜蛋白或肿瘤细胞。本发明进一步涉及形成具有膜融合活性的重组膜膜的方法,该膜膜是脂质双层膜,优选包含病毒的天然脂质,病毒融合蛋白,一种或多种任选的另外的抗原以及两亲性佐剂。包含这种重构的病毒膜的药物组合物也是本发明的一部分。

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