bacterial destruction method in a patient treatment area and antimicrobial photodynamic therapy composition

摘要

"BACTERIA DESTRUCTION METHOD IN A PATIENT TREATMENT AREA AND ANTIMICROBIAN COMPOSITION OF PHOTODYNAMIC THERAPY". A method and composition for destroying microbes, especially bacteria, in the body using Erythrosin B along with electromagnetic radiation is disclosed. In a preferred method, a composition comprising Erythrosine B is introduced into a treatment area. After sufficient time has elapsed, radiation of an appropriate wavelength is applied to the area to activate Erythrosin B and, by a photodynamic reaction, destroy the bacteria. Preferred radiation has a wavelength around 530 nm. Erythrosin B is incorporated into a gel, which acts to restrict the photodynamic action close to the biofilm, thereby ensuring that only unwanted bacteria is affected and the natural microfiora is unharmed. This method is effective for killing at least Gram-positive bacteria and is particularly effective in areas where complex media such as saliva are also present.