Synthesis Procedure of selective drivados 2-amino-5 - (trifluoromethyl - in the presence of a Lewis acid

摘要

1. - a method for preparing formula compounds, wherein X2 is a latex group, R3 and R4 are substitutes independently selected from hydrogen, aromatic group and crystalline group, or both nr3r4 can form an aromatic or crystalline ring with 4-11 members, wherein the method adopted is: Among them, an equation 10 compound and an equation 3 amine (hnr3r4) react with Lewis acid and a non nuclear basis to form an equation 11 compound, in which X1 is a group l.2.Independently select a method for the second claim from the mixture of halide, arilsulfonato, asphalt, perfluoroalkyl sulfonate, arilsulfonato or asphalt, wherein X1 and X2 are the same or different, and each method is an independent halide. X2 is clorous. 5. - a method of claim 1, in which hr3r4 is an aromatic amine using a 0.25-10 equivalent of Lewis acid compared to the amount of pyridine 10.6.This is an aromatic amine. Compared with 10.7% pyridine, 0.5-3 of Lewis acid is used, among which Lewis acid is a metal ion salt selected from Zn ion, Mg, Sn, Ti, Al, s, Li, Ag and Cu ion groups.