首页> 外国专利> Monohydrochloride - dione (2.5 - 3 - 1 - methyl - 1H indole - 3 - yl) - 4 - 1 - (2 - pyridin - ylmethyl) piperidin-4-yl il - 1H indole - 3 - yl - 1H - pi - coming Four Lens

Monohydrochloride - dione (2.5 - 3 - 1 - methyl - 1H indole - 3 - yl) - 4 - 1 - (2 - pyridin - ylmethyl) piperidin-4-yl il - 1H indole - 3 - yl - 1H - pi - coming Four Lens

机译:一盐酸盐-二酮(2.5-3-1-甲基-1H吲哚-3-yl)-4-[1-(2-吡啶-ylmethyl)哌啶4 -yl il]-1H吲哚-3-yl]-1H- pi-即将推出的四镜头

摘要

Monohydrochloride - dione 1 - 2.5 - 3 - (1 - methyl - 1H indole - 3 - yl) - 4 - [1 - (2 - pyridin - ylmethyl) piperidin-4-yl il] - 1H indole - 3 - yl] - 1H pyrrole Crystalline hydrate thereof or mixtures the mismos.2.Monohydrochloride - dione - 2.5 - 3 - (1 - methyl - 1H indole - 3 - yl) - 4 - [1 - (2 - pyridin - ylmethyl) piperidin-4-yl il] - 1H indole - 3 - yl] - 1H pyrrole Crystalline hydrate thereof, or mixtures of the same, that is a model of x-ray diffraction Peaks that includes the following: 6.8 + 10.9 + 0.1, 0.1, 0.1 and 14.2 + 16.6 + 0,1 in 2? When the model is derived from a Radiation source of copper (Cuka;? Three. - a) = 154056 monohydrochloride Crystal claims that a model of x-ray diffraction Peaks, which also includes the following: 6.3 7.2 + + 0.1, 0.1, 0.1 and 0,1u00b0 17.0 + 12.5 + 2? 4.A Pharmaceutical composition comprising a Salt of any of claims 1 - 3 and a vehicle farmacu00e9utico.5. - A method of treatment of lymphomas are non Hodgkin's - which comprises administering to a Mammal in need an effective amount of a composed Or to any one of claims 1 - 3.
机译:单盐酸盐-二酮1-2.5-3-(1-甲基-1H吲哚-3-yl)-4-[1-(2-吡啶基-甲基)哌啶-4-基il]-1H吲哚-3-yl]- 1H吡咯结晶水合物或其混合物2.一盐酸盐-二酮-2.5-3-(1-甲基-1H吲哚-3-yl)-4-[1-(2-吡啶-ylmethyl)哌啶-4-基il]-1H吲哚-3-yl]-1H吡咯结晶水合物或其混合物,是X射线衍射峰的模型,其中包括:6.8 + 10.9 + 0.1、0.1、0.1和14.2 + 16.6 + 0,1 in 2?当该模型源自铜的辐射源(Cuka ;?三。-a)= 154056一盐酸盐时,晶体声称该模型具有x射线衍射峰,该模型还包括以下内容:6.3 7.2 + + 0.1、0.1、0.1和0,1 u00b0 17.0 + 12.5 + 2? 4.药物组合物,其包含权利要求1-3中任一项的盐和媒介物farmac u00e9utico.5。 -非霍奇金淋巴瘤的治疗方法-该方法包括对需要的哺乳动物施用有效量的权利要求1-3中任一项的组合物。

著录项

  • 公开/公告号CO5680446A2

    专利类型

  • 公开/公告日2006-09-29

    原文格式PDF

  • 申请/专利权人 ELI LILLY AND COMPANY;

    申请/专利号CO20050001481

  • 发明设计人 REUTZEL-EDENS SUSAN MARIE;

    申请日2005-01-11

  • 分类号A61K31/4468;

  • 国家 CO

  • 入库时间 2022-08-21 21:39:53

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