首页> 外国专利> IMIDAZOPIRIDIN-SUBSTITUTE TROPANE DERIVATIVES, possessing the activity of the antagonist CCR5 Receptor, for the treatment of the human immunodeficiency virus (HIV) and inflammation

IMIDAZOPIRIDIN-SUBSTITUTE TROPANE DERIVATIVES, possessing the activity of the antagonist CCR5 Receptor, for the treatment of the human immunodeficiency virus (HIV) and inflammation

机译:具有拮抗CCR5受体活性的咪唑啉取代素取代的戊烷衍生物,可用于治疗人类免疫缺陷病毒(HIV)和炎症

摘要

The present invention provides compounds of formula (I), where R and R are as defined in the description. The compounds of the present invention are modulators, in particular antagonists, of chemokine CCR5 receptor activities. Modulators of the CCR5 receptor can be useful in the treatment of various inflammatory diseases and conditions, as well as in the treatment of HIV infection and infection caused by genetically related retroviruses.
机译:本发明提供式(I)的化合物,其中R 1和R 2如说明书中所定义。本发明的化合物是趋化因子CCR5受体活性的调节剂,特别是拮抗剂。 CCR5受体的调节剂可用于治疗各种炎性疾病和病症,以及用于治疗HIV感染和由遗传相关逆转录病毒引起的感染。

著录项

  • 公开/公告号EA200600480A1

    专利类型

  • 公开/公告日2006-08-25

    原文格式PDF

  • 申请/专利权人 ПФАЙЗЕР ИНК.;

    申请/专利号EA20060000480

  • 发明设计人 СТАППЛ ПОЛ ЭНТОНИ;

    申请日2004-09-28

  • 分类号C07D471/04;A61K31/4188;A61K31/4745;A61P31/18;C07D471/02;C07D519;

  • 国家 EA

  • 入库时间 2022-08-21 21:39:36

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