A NOVEL FREE RADICAL NITROSYL-HYDROXYL-HEMATIN FOR OXIDATIVE DECONTAMINATION OF WARFARE CHEMICAL AND BIOLOGICAL AGENTS

摘要

The present invention is referred in a method for the inhibition of the growth of bacteria, bacterial spores, inactivation of bacterial toxins, inactivation of viruses. The present invention provides compositions of oxidative agents that possess unexpected synergistic activity against microorganisms. Peroxynirite (ONOO) shen combined with hematin forms the strong stable radical hematin-Fe-(HO)ONOO2-. The present invention also provides a composition and method for decontamination processes. The composition of the present invention includes sufficient amounts of hematin-Fe-(HO)ONOO2- and/ or the combination fo ONOO- in an alkaline solution of lithium hydroxide (LiOH) and a oxidizing biocide like the mild oxidizer selenium dioxide (SeO2),the peracetic acid or peroxyacety nitrate. Acid decomposition of ONOO- is a non-halogen, oxidizing biocide which is effective against microbes and can replace common non-oxidizing biocides such as isothiozolone and glutaraldehyde as well as oxidizing biocides such as peracetic acid while providing technical and cost performance. Although a potent biocide ONOO- degrades to environmentally innocuous NO2- and H2O..