NOVEL INDENO2,1aINDENE AND ISOINDOLO2,1- aINDOLES AS THERAPEUTICS AGENTS PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

摘要

The present invention describes Indeno[2,1a]indene and isoindolo[2,1-a]indole derivatives, of the Formula (I), its salts and its stereoisomers, wherein X, R1, R2, R3, R4, R6, R7, Rs, Rg, R11, R12, R13 and R14 are as described in the specification. Formula (I) The invention also provides a method to prepare compound with formula (I), pharmaceutical composition containing such compounds and method to manufacture a medicament. These compounds are useful in the treatment of various CNS disorders, hematological disorders, eating disorders, diseases associated with pain, respiratory diseases, genito-urological disorders, cardio vascular diseases and cancer.