COMPOSITIONS OF A BENZENESULFONAMIDE OR METHYLSULFONYLBENZENE CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A CHOLINERGIC AGENT FOR THE TREATMENT OF REDUCED BLOOD FLOW OR TRAUMA TO THE CENTRAL NERVOUS SYSTEM.

摘要

The present invention provides methods and compositions for the treatment of central nervous system damage in a subject. More particularly, the invention provides a combination therapy for the treatment of a central nervous system ischemic condition or a central nervous system traumatic injury comprising the administration to a subject of a cholinergic agent in combination with a benzenesulfonamide or methylsulfonylbenzene cyclooxygenase-2 selective inhibitor.