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Compositions of fine solid particles of selective PDE4 inhibitors for delivery to the lungs by inhalation
Compositions of fine solid particles of selective PDE4 inhibitors for delivery to the lungs by inhalation
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机译:选择性PDE4抑制剂的细小固体颗粒成分,可通过吸入传递到肺部
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摘要
Described is an inhaled formulation comprising 9-cyclopentyl-5,6-dihydro-7-ethyl-3-(thien-2-yl)-9H-pyrazolo[3,4-c]1,2,4-triazolo[4,3-alpha]pyridine or a pharmaceutically acceptable salt thereof, wherein the formulation is capable of delivering the compound as solid particles to the lung. The particles are less than 20 micrometers in diameter and the formulation is capable of being delivered to the lung by a dry powder inhaler. This inhaled formulation can be used in the manufacture of a medicament for the treatment of a disease treatable by the inhibition of PDE4 such as a respiratory disease, for example asthma or chronic obstructive pulmonary disease.
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