首页> 外国专利> Use of hydroxylamine derivative in the preparation of a pharmaceutical or cosmetical composition for increasing expression of molecular chaperons, hydroxylamine derivative and pharmaceutical and/or cosmetical compositions comprising the said compound

Use of hydroxylamine derivative in the preparation of a pharmaceutical or cosmetical composition for increasing expression of molecular chaperons, hydroxylamine derivative and pharmaceutical and/or cosmetical compositions comprising the said compound

机译:羟胺衍生物在制备用于增加分子伴侣的表达的药物或化妆品组合物中的用途,羟胺衍生物以及包含所述化合物的药物和/或化妆品组合物

摘要

Described is use of a chemical compound in the preparation of a pharmaceutical composition for increasing expression of molecular chaperons expresses by a cell or an eukaryotic cell that is exposed to a physiological stress to increase the expression of the molecular chaperon by the cell beyond the amount induced by the physiological stress or for the treatment of a disease connected with the function of the chaperon system or associated with the injury of the membrane of a cell or cell organellum, or optionally preventing the same, wherein the chemical compound is a hydroxylamine derivative the tautomeric forms of which are represented by formulae (I) and (II), or its salt and/or an optically active stereoisomer thereof. Described is also mentioned hydroxylamine derivative and pharmaceutical and/or cosmetical compositions comprising the said compound.
机译:描述了化合物在制备药物组合物中的用途,该药物组合物用于增加暴露于生理应激的细胞或真核细胞表达的分子伴侣的表达,从而使细胞增加分子伴侣的表达,使其超过诱导量。通过生理应激或用于治疗与伴侣系统功能有关或与细胞或细胞器细胞膜受损相关的疾病,或任选地预防疾病的方法,其中化合物为羟胺衍生物或互变异构体其形式由式(I)和(II)表示,或其盐和/或其旋光性立体异构体。还描述了羟胺衍生物和包含所述化合物的药物和/或化妆品组合物。

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