首页>
外国专利>
PROPANE-1,3-DISULPHONIC ACID AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS FOR THE TREATMENT OF AMYLOIDOSIS
PROPANE-1,3-DISULPHONIC ACID AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS FOR THE TREATMENT OF AMYLOIDOSIS
展开▼
机译:丙烷-1,3-二硫代酸及其药学可接受的盐治疗淀粉样变性病
展开▼
页面导航
摘要
著录项
相似文献
摘要
Therapeutic compounds and methods for inhibiting amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is inhibited by the administration to a subject of an effective amount of a therapeutic compound comprising an anionic group and a carrier molecule, or a pharmaceutically acceptable salt thereof, such that an interaction between an amyloidogenic protein and a basement membrane constituent is inhibited. Preferred anionic groups are sulfonates and sulfates. Preferred carrier molecules include carbohydrates, polymers, peptides, peptide derivatives, aliphatic groups, alicyclic groups, heterocyclic groups, aromatic groups and combinations thereof. IMAGE
展开▼