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SEMI-ALLOGENIC ANTITUMOR VACCINE WITH HLA-HAPLO-IDENTICAL ANTIGEN-PRESENTING CELLS
SEMI-ALLOGENIC ANTITUMOR VACCINE WITH HLA-HAPLO-IDENTICAL ANTIGEN-PRESENTING CELLS
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机译:带有HLA-HAPLO抗原递呈细胞的半同种抗原疫苗
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摘要
The present invention relates to semi-allogeneic antigen-presenting cells into which proteins and/or peptides or RNA or DNA or cDNA, respectively, encoding said proteins and/or peptides which are overexpressed in tumor cells or which are derived from autologous tumor cells or different tumor cells or different tumor cell lines have been introduced. Furthermore the invention relates to methods for the generation of these semi-allogeneic antigen-presenting cells as well as to the use thereof in the treatment of tumor diseases.
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