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PREPARATION FOR TRANSMISSION OF THE ACTIVE TUMOR-SPECIFIC IMMUNIZATION OF AN IMMUNIZED ALLOGENIC BONE MARKET DISPENSER

机译:免疫同种异体骨市场分配器主动进行肿瘤特异性免疫的制备

摘要

This invention provides a method of improving a transplantation of hematopoietic cells from a donor to a recipient to treat a hematopoietic cell tumor in the recipient comprising immunizing the donor's hematopoietic cells with an antigen specific for the recipient's hematopoietic cell tumor, and transplanting the donor's immunized hematopoietic cells to the recipient. Also provided is a composition comprising purified hematopoietic cells primed to produce an immunological response to foreign tumor specific antigen. Also provided is a method of treating a tumor by the transplantation of hematopoietic cells from a donor to a recipient to treat the tumor in the recipient comprising immunizing the donor's hematopoietic cells with an antigen specific for the recipient's tumor, and transplanting the donor's immunized hematopoietic cells to the recipient.
机译:本发明提供了一种改进从供体到受体的造血细胞移植以治疗受体中造血细胞瘤的方法,该方法包括用对受体的造血细胞瘤特异的抗原免疫供体的造血细胞,并移植供体的免疫的造血细胞。细胞到接收者。还提供了包含纯化的造血细胞的组合物,所述纯化的造血细胞被引发以产生对外来肿瘤特异性抗原的免疫应答。还提供了一种通过将供体的造血细胞移植到接受者以治疗接受者中的肿瘤来治疗肿瘤的方法,该方法包括用对接受者的肿瘤具有特异性的抗原免疫供者的造血细胞,并移植供者的免疫的造血细胞。给收件人。

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