首页> 外国专利> Preparation useful e.g. to treat dry mucous membrane in oral and throat area comprises medical and/or food organic substance, flavor material, mucoadhesive substance, sugar (alcohol) and carrier substance e.g. fat and/or oil

Preparation useful e.g. to treat dry mucous membrane in oral and throat area comprises medical and/or food organic substance, flavor material, mucoadhesive substance, sugar (alcohol) and carrier substance e.g. fat and/or oil

机译:准备有用例如用于治疗口腔和咽喉区域的干燥粘膜的物质包括医疗和/或食品有机物质,调味料,粘膜粘附物质,糖(酒精)和载体物质,例如脂肪和/或油

摘要

Preparation (I) for the treatment of dry mucous membrane in the oral and throat area, which is accompanied by negative conditions e.g. swallowing difficulties, comprises at least a medically compatible and/or food organic substance; at least a medically compatible and/or food regulating certified flavor material; mucoadhesive substance; a sugar and sugar alcohol; and a carrier substance such as fat and/or oil and further a linking agent such as triglyceride and/or hydrophobic liquid, which exhibits lubricating action. Preparation for the treatment of dry mucous membrane in the oral and throat area, which is accompanied by negative conditions such as swallowing difficulties, foreign body sensation in the neck area and pharyngitis, comprises at least a medically compatible and/or food regulating organic substance (15-60 (preferably 20-25)%) such as citric acid, tartaric acid, maleic acid, gluconic acid, ascorbic acid, succinic acid or adipic acid, as a salivation promoting substance (5-25 (preferably 10-20)%); at least medically compatible and/or food regulating certified flavor material; at least a mucoadhesive substance (25-70 (preferably 50-65)%) such as modified cellulose, hydroxymethyl, hydroxyethyl, hydroxypropyl, hydroxypropylmethyl and sodiumcarboxymethylcellulose, polyvinylpyrrolidone, polyethyleneglycol, tragacanth, gum arabic, gelatin, agar-agar, polyacrylic acid and/or polycarbophil; a sugar and sugar alcohol such as glucose, fructose, mannose, maltose, sorbitol, xylitol, mannitol, and synthetic sweetener (saccharin, acesulfame, cyclamate, aspartame and/or its salts); and a carrier substance such as fat and/or oil (almond oil, peanut oil, olive oil, sesame oil, linseed oil, rapeseed oil, mawseed oil, behen oil, and/or neutral oil), and further a linking agent (triglyceride and/or hydrophobic liquid (silicone oil, liquid paraffins and/or low fatty acids (preferably isopropyl myristate, isopropyl palmitate, ethyl and/or oleyl oleate)), which exhibits lubricating action, where (I) is present as gel and in amount of 0.5-5 (preferably 2-3)%. Independent claims are included for: (1) a dental prosthesis-adhesive cream and/or hard gel comprising (I); and (2) a carrier substance of fat and/or oil useful in the manufacture of (I) for mouth area and disrupted area. ACTIVITY : None given. MECHANISM OF ACTION : None given.
机译:用于治疗口腔和咽喉区域的干燥粘膜的制剂(I),其伴有不利条件,例如:吞咽困难,至少包括医学上相容的和/或食品有机物质;至少具有医学相容性和/或食品监管认证的调味料;粘膜粘附物质;糖和糖醇;以及具有润滑作用的载体物质,例如脂肪和/或油,以及另外的连接剂,例如甘油三酸酯和/或疏水性液体。用于治疗口腔和咽喉区域粘膜干燥的制剂,其伴有诸如吞咽困难,颈部区域异物感和咽炎之类的不利条件,至少应包含医学相容性和/或食物调节性有机物质(作为促进流涎的物质,例如柠檬酸,酒石酸,马来酸,葡萄糖酸,抗坏血酸,琥珀酸或己二酸等15-60(优选20-25)%(5-25(优选10-20)%) );至少具有医学相容性和/或食品监管认证的调味料;至少一种粘膜粘附物质(25-70(优选50-65)%),例如改性纤维素,羟甲基,羟乙基,羟丙基,羟丙基甲基和羧甲基纤维素钠,聚乙烯吡咯烷酮,聚乙二醇,黄aga胶,阿拉伯胶,明胶,琼脂,聚丙烯酸和/或聚卡波非;糖和糖醇,例如葡萄糖,果糖,甘露糖,麦芽糖,山梨糖醇,木糖醇,甘露糖醇和合成甜味剂(糖精,乙酰磺胺酸,甜蜜素,阿斯巴甜和/或其盐);和载体物质,例如脂肪和/或油(杏仁油,花生油,橄榄油,芝麻油,亚麻子油,菜籽油,花椒油,山hen油和/或中性油),以及另外的连接剂(甘油三酸酯)和/或具有润滑作用的疏水性液体(硅油,液体石蜡和/或低脂肪酸(最好是肉豆蔻酸异丙酯,棕榈酸异丙酯,油酸乙酯和/或油酸乙酯)),其中(I)呈凝胶状且以一定量存在占0.5-5(最好2-3)%的比例,包括以下方面的独立权利要求:(1)包含(I)的假牙胶和/或硬​​凝胶;和(2)脂肪和/或油的载体物质活性:未给出动作机理:未给出。

著录项

  • 公开/公告号AT414095B

    专利类型

  • 公开/公告日2006-09-15

    原文格式PDF

  • 申请/专利权人 GEBRO PHARMA GMBH;

    申请/专利号AT20030000373

  • 发明设计人

    申请日2003-03-11

  • 分类号A61K31/19;A61K47/30;A61K47/44;

  • 国家 AT

  • 入库时间 2022-08-21 21:36:14

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