CONFORMATIONALLY CONSTRAINED AMINO ACID COMPOUNDS HAVING AFFINITY FOR THE ALPHA2DELTA SUBUNIT OF A CALCIUM CHANNEL

摘要

Novel substituted amino acids of formulae (I) to (VIII) are disclosed and areuseful as agents in the treatment of epilepsy, faintnessattacks, hypokinesia, cranial disorders, neurodegenerative disorders,depression, anxiety, panic, pain, and neuropathological disorders.Processes for the preparation and intermediates useful in the preparation arealso disclosed.