PROTEIN C AND ENDOTHELIAL PROTEIN C RECEPTOR POLYMORPHISMS AS INDICATORS OF PATIENT OUTCOME

摘要

The invention provides methods and kits for obtaining a prognosis for apatient having orat risk of developing an inflammatory condition. The method generallycomprisesdetermining a protein C and/or EPCR genotype(s) of a patient for apolymorphisms in thethese genes, comparing the determined genotype with known genotypes for thepolymorphism that correspond with the ability of the patient to recover fromtheinflammatory condition and identifying patients based on their prognosis. Theinventionalso provides for methods of identifying other polymorphisms that correspondwith theability of the patient to recover from the inflammatory condition.