HIGH-THROUGHPUT SCREENING HIT SELECTION SYSTEM AND METHOD

摘要

A high-throughput screening system and method employing compound relationshipcharacteristics for facilitating hit selection may significantly improve hitconfirmation rate and allow direct identification of active compound familiesexhibiting a certain level of SAR or other relationship characteristic.Valuable family and SAR information obtained at an early stage of the hit-to-lead process may facilitate identification of high quality lead series andcontribute to the overall success rate of drug discovery processes.