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Improved transdermal therapeutic system for the treatment of Parkinson's disease
Improved transdermal therapeutic system for the treatment of Parkinson's disease
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机译:改良的经皮治疗系统,用于治疗帕金森氏病
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摘要
This invention provides the use of a silicone-based transdermal therapeutic system having an area of 10 to 40 cm2 and containing 0.1 to 3.15 mg / cm2 of Rotigotine as active ingredient, for the preparation of an anti-Parkinson medicament which effects an improvement, compared to a placebo treatment, of the condition of human Parkinson patients, measured according to the Unified Parkinson's Disease Rating Scale (UPDRS) parts II and III, of 2 units or more following administration for a time period of at least 7 weeks.
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机译:本发明提供了面积为10至40cm 2且含有0.1至3.15mg / cm 2罗替戈汀作为活性成分的基于硅氧烷的透皮治疗系统在制备抗帕金森氏药物中的用途。与安慰剂治疗相比,根据帕金森病综合评分量表(UPDRS)第II部分和第III部分测得的人类帕金森病患者的病情在服用至少2个月后至少改善了2个单位或更多7周。
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