MODULATION OF MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 11 EXPRESSION

摘要

Compounds, compositions and methods are provided for modulating the expression of mitogen-activated protein kinase kinase kinase 11. The compositions comprise oligonucleotides, targeted to nucleic acid encoding mitogen-activated protein kinase kinase kinase 11. Methods of using these compounds for modulation of mitogen-activated protein kinase kinase kinase 11 expression and for diagnosis and treatment of disease associated with expression of mitogen­activated protein kinase kinase kinase 11 are provided.