CANDIDATE GENES, PATHWAYS AND MECHANISMS FOR BIPOLAR AND RELATED DISORDERS

摘要

Identification of nucleic acids and gene expression profiles involved in neuropsychiatric disorders (e.g., bipolar and related disorders), and the use of such expression profiles and nucleic acids in methods for identifying candidate agents which modulate neuropsychiatric disorders or neuropsychiatric disorder susceptibility. Methods and reagents for the diagnosis and treatment of neuropsychiatric disorders. Methods for the diagnosis of neuropsychiatric disorders and susceptibility to neuropsychiatric disorders by detecting polymorphisms, mutations, variations, alterations in expression, and the like, in neuropsychiatric disorder-related genes, or polymorphisms linked to these genes. Compositions and methods for treating neuropsychiatric disorders or neuropsychiatric disorder susceptibility. Pharmaceutical compositions for treating a neuropsychiatric disorder or neuropsychiatric disorder susceptibility are provided.