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DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH CXC CHEMOKINE RECEPTOR 1 (CXCR1)
DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH CXC CHEMOKINE RECEPTOR 1 (CXCR1)
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机译:CXC趋化因子受体1(CXCR1)相关疾病的诊断和治疗
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摘要
The invention provides a human CXCR1 which is associated with the cardiovascular disorders, gastrointestinal and liver diseases, metabolic diseases, inflammatory diseases, hematological disorders, respiratory diseases, neurological disorders, urological Disorders, cancer disorders and reproduction disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, gastrointestinal and liver diseases, metabolic diseases, inflammatory diseases, hematological disorders, respiratory diseases, neurological disorders, urological Disorders, cancer disorders and reproduction disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of CXCR1 as well as pharmaceutical compositions comprising such compounds.
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