ANTITUMOR AGENT, METHOD OF PRODUCING ANTITUMOR AGENT, MEDICINAL COMPOSITION CONTAINING ANTITUMOR AGENT AND MICROORGANISM PRODUCING ANTITUMOR AGENT

摘要

It is intended to provide an antitumor agent, which has established a strengthened function selectivity of acting exclusively on caner cells, lessened side effects, mastery of drug tolerance and so on, and has an activity of inducing cell death in human lung small cell carcinoma Ms-1 cells and human lung small cell carcinoma Ms-1/Bcl-2 cells and Ms-1/Bcl-XL cells with the overexpression of an apoptosis-inhibitory protein Bcl-2 or Bcl-XL, and so on. Namely, an antitumor agent characterized by being a compound represented by the following general formula or its derivative. [Chemical formula 12] wherein R represents a hydrogen atom or an alkyl group.