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COMPOSITIONS AND USE OF INFLAMMATION-20 (INF-20) GENE
COMPOSITIONS AND USE OF INFLAMMATION-20 (INF-20) GENE
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机译:INFLAMMATION-20(INF-20)基因的组成和用途
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摘要
This invention relates to Inf-20, a novel apoptosis regulator, that in one embodiment is induced by TNF. The gene, designated inflammation-20 (Inf-20), encodes a polypeptide of 184 amino acids. In one embodiment Inf-20 comprises a conserved death effector domain (DED) that is capable of interacting with caspase-8, but not with Fas-associated death domain (FADD) protein.
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