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PEPTIDES ASSOCIATED WITH HLA-DR MHC CLASS II MOLECULES INVOLVED IN AUTOIMMUNE DISEASES
PEPTIDES ASSOCIATED WITH HLA-DR MHC CLASS II MOLECULES INVOLVED IN AUTOIMMUNE DISEASES
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机译:与自身免疫性疾病相关的HLA-DR MHC CLASS II分子相关的肽
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摘要
Antigenic peptides that bind to MHC Class II molecules with the shared epitope referred to as HLA-DR molecules are disclosed. More specifically, are citrullinated antigenic peptides having an increased affinity for HLA-DR molecules and associated with Rheumatoid arthritis. These novel peptides provide the basis for new methods of diagnosis and treatment of Rheumatoid arthritis.
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