TOLL-LIKE RECEPTOR 3, ITS SIGNALLING ASSOCIATED MOLECULE TRIF AND THEIR USE IN THE PREVENTION AND TREATMENT OF HOST INFLAMMATION RESPONSE INDUCED BY A RNA VIRUS

摘要

The present invention relates to toll-like receptor 3 (TLR3) and its signalling associated molecule TRIF. More specifically, the present invention relates to screening methods for the identification of TLR3 and TRIF antagonists and methods for treating and/or preventing host inflammation response induced by a RNA virus.