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METHODS OF PROMOTING HEALING OF CARTILAGE DEFECTS AND METHOD OF CAUSING STEM CELLS TO DIFFERENTIATE BY THE ARTICULAR CHONDROCYTE PATHWAY
METHODS OF PROMOTING HEALING OF CARTILAGE DEFECTS AND METHOD OF CAUSING STEM CELLS TO DIFFERENTIATE BY THE ARTICULAR CHONDROCYTE PATHWAY
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机译:促进软骨缺损愈合的方法和通过软骨细胞通路使干细胞分化的方法
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摘要
Methods of promoting healing of a cartilage defect in a region of cartilage, which comprises the defect and which may further comprise stem cells, and methods of promoting healing of a cartilage defect in a region of cartilage, which comprises the defect and an implant comprising cartilage scaffold or a cartilage graft, which methods comprise contacting the region with various combinations of cartilage fragments, a growth factor, a partially synthesized extracellular matrix, a scaffold, an implant comprising cartilage scaffold, an implant comprising a cartilage graft, stem cells, chondrocytes, a proteoglycan, an anti-oxidant, a collagen precursor, a vitamin, a mineral, and/or a cartilage-degrading enzyme; and a method of causing stem cells to differentiate by the articular chondrocyte pathway comprising contacting the stem cells with a compound comprising an active alcohol moiety.
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