TREATMENT OF INSULIN RESISTANCE BY MODULATING SOMATOSTATIN USING SOMATOSTATIN RECEPTOR ANTAGONISTS

摘要

The present invention provides the use of somatostatin antagonists for treating and preventing hepatic insulin sensitizing substance (HΙSS)-dependent insulin resistance (HDIR) and hemorrhage induced insulin resistance. The present invention further provides pharmaceutical compositions comprising a somatostatin antagonist and a pharmaceutically acceptable liver targetting compound.