DUAL INHIBITORS OF ADIPOCYTE FATTY ACID BINDING PROTEIN AND KERATINOCYTE FATTY ACID BINDING PROTEIN

摘要

Compounds that are dual aP2/k-FABP inhibitors are provided having the formula wherein A, B, X, Y, RSUP1/SUP, RSUP2 /SUPand RSUP3 /SUPare as described herein. A method is also provided for treating diabetes and related diseases, especially Type II diabetes, employing dual aP2/k-FABP inhibitors alone or in combination with at least one other antidiabetic agent such as metformin, glyburide, troglitazone and/or insulin.