RAPAMYCIN COMPOUNDS IN THE TREATMENT OF NEUROFIBROMATOSIS TYPE 1

摘要

The present invention is directed to methods for treating neurofibromatosis type 1 (NFI) using rapamycin, derivatives of rapamycin or prodrugs of rapamycin. The invention covers the treatment both of non-malignant fibromas, as well as a variety of tumors associated with cells that have mutations in the NF1 gene.