A METHOD FOR DETERMINING A RISK OF ATHEROSCLEROSIS OR FUTURE DEVELOPMENT OF ATHEROSCLEROTIC COMPLICATIONS

摘要

The present invention discloses a method for determining a risk of atherosclerosis or future development of atherosclerotic complications by measuring an amount of a soluble Fc gamma receptor IIIaM phi derived from macrophage (hereafter abbreviated as sFc gamma RIIIaM phi ) in a blood sample from patients by using an antibody specifically recognizing Fc gamma RIIIaM phi , and determining the risk on the basis of the result of the measurement, a kit for measuring an amount of sFc gamma RIIIaM phi and a kit for determining a risk of development of atherosclerosis or future development of atherosclerotic complications. ??A determination method of the present invention is a non-invasive method with greatly mitigated patient burden compared with a conventional cardiac catheterization method, because it is a method by measuring an amount of sFc gamma RIIIaM phi in a blood sample, which is a novel predictive marker of atherosclerosis. Furthermore, the present method can also determine a risk of coming down with atherosclerotic complications in the future for a case of superficially healthy but with progressing atherosclerosis internally.