PLASMA POLYMERISATION METHODS FOR THE DEPOSITION OF CHEMICAL GRADIENTS AND SURFACES DISPLAYING A GRADIENT OF IMMOBILISED BIOMOLECULES

摘要

The invention relates to a method to prepare at least part of at least one surface of a substrate comprising depositing on the surface at least one plasma monomer from a monomer source wherein during deposition of said monomer said monomer and/or said surface are moved relative to one another to provide a non-uniform plasma polymerised surface, and introducing to at least part of said plasma polymerised surface a binding entity to provide a non-uniform surface formed from said binding entity.