首页> 外国专利> A METHOD OF EVALUATING ANTICANCER ACTIVITY OF ANTICANCER AGENT USING BY H-RAS OVER-EXPRESSING TRANSGENIC MOUSE

A METHOD OF EVALUATING ANTICANCER ACTIVITY OF ANTICANCER AGENT USING BY H-RAS OVER-EXPRESSING TRANSGENIC MOUSE

机译:用H-RAS过表达转基因小鼠评估抗癌剂抗癌活性的方法

摘要

The present invention is a black, and more particularly, H- Ras (Ras) anti-cancer activity of the anticancer drug after administration by using a transgenic mouse with cancer susceptibility whether the anticancer agent as a method for testing the anticancer activity of the anticancer agent with a transgenic mouse or to a method of measuring the delay effect of the liver cancer.; The invention bar and evaluation of the anticancer activity of the anticancer agent and novel cancer suppression or delay the effect of significantly suppressing the generation of the tumor when administered drug showing the anti-cancer activity in mice over-expressing H- Ras causing H- Ras-derived cancer, including liver cancer a it can be usefully used in the evaluation of the visible material.
机译:本发明是黑色的,更具体地,是通过使用具有癌症易感性的转基因小鼠施用后的抗癌药的H-Ras(Ras)抗癌活性,是否所述抗癌剂作为测试抗癌剂的抗癌活​​性的方法;或与转基因小鼠一起使用的药物或测量肝癌延迟效应的方法。当施用在过量表达引起H-Ras的H-Ras的小鼠中显示抗癌活性的药物时,本发明和抗癌剂的抗癌活​​性的评估以及新型癌症抑制或延迟显着抑制肿瘤发生的效果衍生的癌症,包括肝癌,可用于评估可见物质。

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