首页>
外国专利>
A METHOD OF TREATING HIV INFECTION IN ATAZANAVIR RESISTANT PATIENTS USING A COMBINATION OF ATAZANAVIR AND ANOTHER PROTEASE INHIBITOR
A METHOD OF TREATING HIV INFECTION IN ATAZANAVIR RESISTANT PATIENTS USING A COMBINATION OF ATAZANAVIR AND ANOTHER PROTEASE INHIBITOR
展开▼
机译:阿扎那韦和另一种蛋白酶抑制剂联合治疗抗阿扎那病毒患者的艾滋病毒感染的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method of treating HIV infection in a human patient wherein the infecting HIV strain has become resistant to atazanavir, the method comprising administration of a therapeutically effective amount of a combination of atazanavir or a pharmaceutically acceptable salt thereof, and at least one other HIV protease inhibitor. A method for enhancing the effectiveness of a second HIV protease inhibitor in treating HIV infection in a human patient whose HIV strain has become resistant to atazanavir or a pharmaceutically acceptable salt thereof, comprising administering to said human patient an amount of atazanavir or a pharmaceutically acceptable salt thereof effective in maintaining the resistant strain, in combination with the second HIV protease inhibitor. The resistance to atazanavir in the human is manifested by the existence of the signature mutation consisting of I50L mutation in the HIV protease.
展开▼