NITROOXYDERIVATIVES OF FLUVASTATIN, PRAVASTATIN CERIVASTATIN, ATORVASTATIN AND ROSUVASTATIN AS CHOLESTEROL-REDUCING AGENTS WITH IMPROVED ANTI-INFLAMMATORY, ANTITHROMBOTIC AND ANTIPLATELET ACTIVITY

摘要

Nitrooxyderivatives of fluvastatin, cerivastatin, atorvastatin and rosuvastatin having improved pharmacological activity and enhanced tolerability are described. They can be employed for treating and/or preventing several diseases, in particular coronary syndromes, neurodegenerative disorders as well as for reducing cholesterol levels.