首页>
外国专利>
POLYPEPTIDES FOR MODULATING BINDING OF TRP CHANNEL PROTEINS AND TRP-ASSOCIATED PROTEINS
POLYPEPTIDES FOR MODULATING BINDING OF TRP CHANNEL PROTEINS AND TRP-ASSOCIATED PROTEINS
展开▼
机译:用于调节TRP通道蛋白和TRP结合蛋白结合的多肽
展开▼
页面导航
摘要
著录项
相似文献
摘要
This invention relates to inhibitors and modulators of the binding between a transcient receptor potential (TRP) channel protein and a TRP-associated binding protein. In particular inhibitors and modulators of the binding between the TRPM7 channel protein and PDZ-domain containing TRP-associated proteins. These modulators and inhibitors are used to control Ca2+ transport through TRPM7 channel proteins and reduce damage to mammalian cells, including brain and spinal cord cells, after ischemia or traumatic injury.
展开▼