MOLECULAR DIVERSITY TECHNOLOGY OF QUINAZOLINE LIBRARY BASED ON COMBINATORIAL CHEMISTRY

摘要

The present invention provides a solution -phase synthesis of quinazoline (quinazoline) derivatives such as Formula 1 (solution phase) more easily than the classical synthesis method as a technique to build a chemical method using a combination of molecular diversity , and relates to a reaction method that can quickly produce a pure objective compound in high purity . ; [ formula 1] ; ( wherein R1, R2, R3, and R4 are as defined in the specification )