Method for Preparing Salicin Analogous, the Salicin Analogous therefrom and Blood Coagulation Control Composition Containing the Salicin Analogous

摘要

The invention raised analog method, analogs prepared raised therefrom and directed to a composition for anticoagulants containing them, Lu Pocono stock mesen steroid remove the dextran sucrase from Ajay (Leuconostoc mesenteroides) strains and purifying; 0.01-2M a concentration was added to the dextran sucrase azepin a sugar-containing solution, and then, this 15-by raised in the reactor of 50 ℃, salicyl alcohol and / or phenol and reaction raised the glucose of sugar, salicylate generating an analog raised to transition to the alcohol and / or phenol; And separating and purifying said analogs raised; method analogs prepared consisting of salicylic, including, blood coagulation regulating compositions containing the analogs and the raised raised analogs made from the above method is provided. ; According to the invention the dextran can can be used to Klein azepin be synthesized raised analogs enzymatically, thus synthesized raised similar weight part represents a high blood coagulation-inhibiting effect than aspirin and some high blood coagulation than the raised and water image shows a promoting effect may be useful in regulating blood clotting composition. ; Dextran sucrase kinase, sucrose, aspirin, receptor reactions, blood coagulation