A novel fungal species of Micromucor ramannianus var. angulisporus CRM000232 and protein tyrosin phosphatase 1B inhibitor comprising depside compounds isolated and purified from them

摘要

The present invention relates to novel fungal strain micro myuko Rahman California Nurse VARS anggul lease porous (Micromucor ramannianus var. Angulisporus) CRM000232 (KCTC 10696BP), and this from the isolated and purified by Deb seed compounds as an active ingredient in a protein tyrosine dephosphorylation enzyme 1B relates to inhibitors. ; Deb seed-based compound the separation from mold strains CRM000232 (KCTC 10696BP) according to the invention, tablets are useful for diabetes prevention and treatment as excellent in protein tyrosine dephosphorylation enzyme 1B inhibitory activity, an excellent hypoglycemic effect, in particular, the therapeutic effect is excellent with respect to type 2 diabetes in NIDDM.