首页> 外国专利> MULTISTAGE DIELECTROPHORETIC SEPARATION CHIP, ITS APPLICATION TO MICROFLUIDIC SYSTEM FOR TOTAL BLOOD CELL ANALYSIS, AND ASSAYING METHOD OF THE TOTAL BLOOD CELL USING THEREOF

MULTISTAGE DIELECTROPHORETIC SEPARATION CHIP, ITS APPLICATION TO MICROFLUIDIC SYSTEM FOR TOTAL BLOOD CELL ANALYSIS, AND ASSAYING METHOD OF THE TOTAL BLOOD CELL USING THEREOF

机译:多级介电分离芯片,其在总细胞分析微流控系统中的应用,以及基于该方法的总细胞评估方法

摘要

The present invention relates to a multi-electrophoretic-based microfluidic chip, a microfluidic system for whole blood analysis and a whole blood analysis method employing the same, and more specifically, a cell or microparticle injection unit (1); A bent microfluidic channel portion composed of at least one or more for selectively deflecting the injected cells or microparticles by dielectrophoresis force and separating them into a plurality of cells or microparticles; A microexpansion channel part 3 for separating and separating the deflected cell particles; And multistage dielectrophoresis (MSDEP) -based microfluidic chips, microfluidic systems for whole blood analysis, and the multi-electrophoresis based on the number of discharge parts (4) to (7) as many as the number of cell particles. As for the whole blood analysis method, according to the present invention, unlike the whole blood analysis method which is conventionally performed in a first-line hospital, etc., the cell recovery rate is high and the advantage of being able to quickly and accurately and conveniently characterize whole blood from a very small amount of blood (nl) Have;Multiple Dielectrophoretic Separation Chips, Trapezoidal Electrode Arrays, Micro Expansion Channels, Separation-Based Bioparticle Analysis Systems
机译:本发明涉及基于多电泳的微流体芯片,用于全血分析的微流体系统以及使用该芯片的全血分析方法,更具体地,涉及细胞或微粒注射单元(1)。弯曲的微流体通道部分,其由至少一个或多个组成,用于通过介电泳力选择性地使注入的细胞或微粒偏转并使它们分离成多个细胞或微粒;用于分离并分离偏转的细胞颗粒的微膨胀通道部分3;以及基于多级介电电泳(MSDEP)的微流控芯片,用于全血分析的微流控系统以及基于放电部分(4)至(7)的数量与细胞颗粒数量相同的多电泳。关于全血分析方法,根据本发明,与传统上在一线医院等中进行的全血分析方法不同,细胞回收率高并且具有能够快速且准确地进行的优点。并能从很少的血液(nl)中方便地表征全血;多个介电电泳分离芯片,梯形电极阵列,微膨胀通道,基于分离的生物颗粒分析系统

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