Dermal substitute consisting of amnion and biodegradable polymer, the preparation method and the use thereof

摘要

PURPOSE: Provided is an implantable derma substitute formed of amnion and bio-degradable materials, which has anti-inflammatory effect and an effect of stimulating wound-healing by various growth and differentiation factors. CONSTITUTION: The derma substitute has a composite structure obtained by adhering, incorporating or inserting a bio-compatible amnion separated from a placenta and a bio-degradable polymer substrate each other. Particularly, the bio-degradable polymer is selected from the group consisting of collagen, gelatin, hyaluronic acid or a derivative thereof, chitin, chitosan, PLGA(poly(D,L-lactic-co-glycolic acid)), PGA(polyglycolic acid) and PLA(poly lactic acid).