首页> 外国专利> Formulation having cyclooxygenase inhibiting activity, useful e.g. as antioxidants and to treat pain, liver cirrhosis and Parkinson's disease, comprises components or extracts of Byrsocarpus coccineus and Diodia scandens plants

Formulation having cyclooxygenase inhibiting activity, useful e.g. as antioxidants and to treat pain, liver cirrhosis and Parkinson's disease, comprises components or extracts of Byrsocarpus coccineus and Diodia scandens plants

机译:具有环氧化酶抑制活性的制剂,例如作为抗氧化剂并用于治疗疼痛,肝硬化和帕金森氏病,其成分包括:Byrsocarpus coccineus和Diodia scandens植物的成分或提取物

摘要

Formulation (I), having cyclooxygenase (COX)-1 and COX-2 activity for use in humans and animals, comprises components or extracts of Byrsocarpus coccineus and Diodia Scandens. ACTIVITY : Antiinflammatory; Analgesic; Antirheumatic; Neuroprotective; Nootropic; Antiparkinsonian; Immunosuppressive; Hepatotropic; Antidiabetic; Dermatological; Virucide; Gastrointestinal-Gen.; Antiulcer; Antidiarrheic. MECHANISM OF ACTION : Cyclooxygenase (COX)-1 inhibitor; COX-2 inhibitor. The ability of (I) to inhibit COX-1 and COX-2 activity was tested using biological assays. The results showed that the median inhibitory concentration (IC50) value of (I) for COX-1 and COX-2 was 1 mu g/ml and 32 mu g/ml, respectively.
机译:具有在人和动物中使用的具有环氧合酶(COX)-1和COX-2活性的制剂(I),其包含球果贝类和狄氏dia属的组分或提取物。活性:抗炎;止痛药抗风湿;具有神经保护作用;促智;反帕金森病;免疫抑制肝抗糖尿病皮肤;杀病毒剂;胃肠源抗溃疡;止泻药。作用机理:环氧合酶(COX)-1抑制剂; COX-2抑制剂。使用生物学测定法测试(I)抑制COX-1和COX-2活性的能力。结果表明,(I)对COX-1和COX-2的中位抑制浓度(IC50)值分别为1μg/ ml和32μg/ ml。

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