Device for testing sample liquids, e.g. blood, plasma or urine, comprises a capillary channel, a reagent-containing zone with a device for holding liquid during reaction, and a test zone with a detection chemical

摘要

A device for testing sample liquids (2) with a reaction zone (9) with a reagent (R) on the flat side, a test zone (10) and a device for holding (2) in zone (9) for the dissolution and/or reaction of (R), in which there is a means of producing a straight flow front in (2), and at least 90% of (R) reacts with (2) and is transferrable with it to zone (10), or the concentration of (R) or reaction product in (10) varies by not more than 10%. A device (1) for testing sample liquids (2), with: (a) a channel (3) for taking up and transporting the liquid (2) by means of capillary forces, which has a flat side (4) over which the liquid (2) passes with lateral and/or laminar flow; (b) a reaction zone (9) with a soluble and/or reactive reagent (R) on the flat side (4), which can be completely filled with (2) to define a reaction volume (V) of liquid (2); (c) a test zone (10) formed by the channel (3) and following zone (9); and (d) a device (12) for keeping (2) in the reaction zone (9) temporarily for the dissolution and/or reaction of (R). The device (1) also has a means (16) of producing a minimally curved or straight flow front (F) in the liquid (2); the reagent (R) is soluble in and/or reacts with the defined volume (V) of (2) to the extent of at least 90%, and at least 90% of the dissolved (R) or a reaction product of (R) is transferrable to zone (10) together with (V), or the concentration of dissolved (R) or reaction product within (V) in zone (10) varies by not more than 10%. An independent claim is also included for a method for testing sample liquids (2) with the above device, in which the liquid (2) flows from zone (9) into zone (10) with an at least substantially straight flow front (F) and/or at least without any substantial change in flow cross-section.