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Composition, useful in the preparation of pellets and the multi-particular-presentation form, comprises cefuroximaxetil and carrageenan of the group of lambda carrageenan, tau carrageenan and kappa carrageenan
Composition, useful in the preparation of pellets and the multi-particular-presentation form, comprises cefuroximaxetil and carrageenan of the group of lambda carrageenan, tau carrageenan and kappa carrageenan
Composition comprises cefuroximaxetil and at least one carrageenan of the group of lambda carrageenan, tau carrageenan and kappa carrageenan. Independent claims are included for: (1) preparation of pellets from the composition comprising mixing the cefuroximaxetil, the carrageenan and optionally further content material, preferably tri calcium phosphate and/or sucrose ester, granulating the obtained product, extruding the granulated mixture, optionally spheronizing the extruded mixture and optionally covering the obtained pellets with a gastric juice resistant and/or saliva resistant coat; (2) the pellets, which are obtained by the procedure; (3) a multi-particular, presentation form comprising the composition or the pellets; (4) a presentation system comprising the presentation form in a straw with at least one barrier device to the unique dispensation; (5) a kit from the presentation form and a physiologic compatible transportation liquid with a pH value of =6; (6) a crystalline cefuroximaxetil exhibiting an x-ray diffraction spectrum of 8.3, 10.4, 13, and 25.5 (plusminus 0.2 [deg]2theta ); and (7) a composition comprising amorphous cefuroximaxetil and crystalline cefuroximaxetil, preferably the alpha modification, where the weight ratio is 90:10 to 10:90. ACTIVITY : Respiratory-Gen; Antimicrobial; Uropathic.
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