METHOD FOR THE EVALUATION OF THE INDIVIDUAL RISK OF IRREVERSIBLE NERVE DAMAGE, WHICH INCLUDES STEPS FOR THE QUANTITATIVE DETERMINATION OF PEPSINOGEN I (PGI) AND VITAMIN B12 CONCENTRATIONS

摘要

The present invention is aimed at a method and a kit for identifying an individual at risk for irreversible neurological damage and pernicious anaemia, the method comprising the steps of determining quantitatively the pepsinogen I (PGI) analyte concentrations in a serum sample from said individual, selecting a method specific cut-off value for the said analyte, comparing the analyte concentration so determined to the method-specific cut-off value for the analyte, and determining the B12-vitamin concentration or the concentration of an analyte correlating thereto, in a serum sample from the individual.