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procedures for the identification of ifn beta attractive multiple sclerosis patients by determining the expression of trail

机译:确定步道表达的鉴定ifn beta有吸引力的多发性硬化症患者的方法

摘要

This invention relates to a method for identifying an individual, in particular human, as a positive responder or a non-responder to a type-I Interferon (IFN) therapy, in particular IFN- beta therapy, used in the treatment of Multiple Sclerosis by determining TRAIL gene expression and/or TRAIL protein level. The invention further relates to the use of said method for monitoring IFN therapy in the treatment of Multiple Sclerosis and to a kit for carrying out said method.
机译:本发明涉及一种用于识别个体,特别是人类,该个体对通过治疗多发性硬化症所使用的I型干扰素(IFN)疗法,特别是IFN-β疗法的阳性反应者或非反应者。确定TRAIL基因表达和/或TRAIL蛋白水平。本发明进一步涉及所述方法在多发性硬化症的治疗中监测IFN疗法的用途以及用于实施所述方法的试剂盒。

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