Synthesis of 2 - (methylsulfonyl) - 5 - (trifluoromethyl) - 1,3,4 - thiadiazole in the presence of glacial acetic acid as catalyst

摘要

The present invention provides a process for making thiadiazole sulfones. The present process is used to make 2- (methylsulfonyl)-5- (trifluoromethyl)-1,3,4-thiadiazole. 2- (Methylsulfonyl)-5- (trifluoromethyl)-1,3,4-thiadiazole is made using catalytic oxidation in the presence of a suitable oxidizing agent. The catalyst used for the oxidation reaction is glacial acetic acid.