NON-IRRITIVE SUMMARY FOR THE TREATMENT OF THE ACT AND OTHER HAZARDS

摘要

The invention provides methods and compositions which are mild and nonirritating for reducing and eliminating skin disorders, particularly blemishes and redness associated with acne. The hydroalcoholic compositions of the invention contain a keratolytic compound, preferably a beta-hydroxy carboxylic acid, more preferably salicylic acid or pharmaceutically acceptable salt thereof; and a glycerophosphate ester or salt, formulated with pharmaceutically acceptable carriers. Preferred glycerophosphate salts for use in the methods and compositions of the invention are sodium glycerophosphate and calcium glycerophosphate. Additional anti-irritancy agents are not required in the compositions of the present invention, as the glycerophosphate salt component uniquely endows the compositions with nonirritant properties. Other components which may be formulated into the compositions of the invention include fragrances, colorants, emollients, humectants and antimicrobial agents.