use of the antibody 271.14d9.f8 (dsm acc2331) for binding between alphavbeta6 - integrin and fibronectin to inhibit in vitro

摘要

The invention relates to a novel monoclonal antibody and a hybridoma cell line producing said antibody. The monoclonal antibody, a preferred embodiment of which is named 14D9.F8, has the following properties: reacting only with the alpha v-chain of human alpha v-integrins, and inhibiting selectively the attachment to the integrin substrate fibronectin of the alpha v beta 6-integrin bearing cell.