Particles coated prolonged release tablets and their method of preparation and tablets containing them,

摘要

Prolonged-release coated particles (A), consisting of a core (a) containing active agent(s) (I) and binder(s) (II) and a coating film (b) of cellulosic polymer (III) (optionally mixed with plasticizer(s)), additionally include a protective film (c) (covering the film (b)) based on thermoplastic material(s) (IV) of m.pt. 25-100 degrees C. Independent claims are included for: (1) multiparticulate tablets (B), based on (A) and also containing disintegrating and/or swelling agents, diluents, lubricants and optionally antistatic, permeabilizing, sweetening, aromas or colorants; and (2) preparation of (A) and (B).